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Ovary [38], indicating a possibly different role of ALDH1 in ovarian cancer. Our present immunohistochemical study of 248 wellcharacterized patients showed high levels of ALDH1 expression in ovarian carcinoma cells, which were observed in 15.7 of the total cases, was associated with early-stage tumor, well-differentiated tumor and better survivals, although ALDH1 was not an independent risk fac
Ovary [38], indicating a possibly different role of ALDH1 in ovarian cancer. Our present immunohistochemical study of 248 wellcharacterized patients showed high levels of ALDH1 expression in ovarian carcinoma cells, which were observed in 15.7 of the total cases, was associated with early-stage tumor, well-differentiated tumor and better survivals, although ALDH1 was not an independent risk fac
Ovary [38], indicating a possibly different role of ALDH1 in ovarian cancer. Our present immunohistochemical study of 248 wellcharacterized patients showed high levels of ALDH1 expression in ovarian carcinoma cells, which were observed in 15.7 of the total cases, was associated with early-stage tumor, well-differentiated tumor and better survivals, although ALDH1 was not an independent risk fac
Etc. [34, 35]. However, it still remains challenging to identify one single marker or several combined markers to specifically identify all the CSCs in ovarian tumor, and the exact roles of these `stemness' related markers, are still poorly understood due to either a current lack of understanding of the biological functions of the markers, or frequently the lack of information correlating the var
He University of Texas MD Anderson Cancer Center. In their long-term follow-up study, The same mouse monoclonal anti-human ALDH Clone 44 from BD Transduction LaboratoriesTM was used, and it turned out that high level of ALDH1 was detected in 19 out of the total 442 ovarian carcinoma samples, and it was significantly associated with endometrioid adenocarcinoma, early-stage tumor, complete respon
Arian CSCs include CD44, epithelial cell adhesion moleculeHuang et al. BMC Cancer (2015) 15:Page 6 ofTable 3 The associations of ALDH1 expression levels in stromal cells and the clinical and pathologic characteristicsALDH1 IHC score in stromal cells 1 (negative) Number Age (years old): 39 40?9 50?9 60?9 70 missing Histological subtype: Serous carcinoma Mucinous carcinoma Endometrioid carcinoma Cl
Ovary [38], indicating a possibly different role of ALDH1 in ovarian cancer. Our present immunohistochemical study of 248 wellcharacterized patients showed high levels of ALDH1 expression in ovarian carcinoma cells, which were observed in 15.7 of the total cases, was associated with early-stage tumor, well-differentiated tumor and better survivals, although ALDH1 was not an independent risk fac
Sion and Negative groups (p < 0.05, Kaplan-Meier). b High expression level of ALDH1 in tumor cells in ovarian carcinomas was significantly associated with high PFS probabilities (p < 0.05, Kaplan-Meier). c The expression level of ALDH1 in the stromal cells in ovarian carcinoma had no significant association with OS probabilities (p > 0.05, Kaplan-Meier). d No statistical association was found bet

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