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In future modifications of phenotypic criteria. Summary The strengths of the study include the use of proposed DSM-5 criteria for distinguishing youth with AIS from NS;6,10?2 both parents and teachers as informants; large, heterogeneous, clinic-based sample; broad age range (stratified as 6?1 years and 12?8 years); and a diverse array of background and clinical characteristics. Nevertheless, we d
Nvironmental variables that in turn influence informant perceptions of symptom severity, (a) the characteristics of the emotional response are correlated within setting and (b) the expression of anger, anxiety, and depression likely share common neurobiologic pathways.NIH-PA Author Manuscript NIH-PA Author Manuscript NIH-PA Author ManuscriptJ Am Acad Child Adolesc Psychiatry. Author manuscript; a
,3,4,32 and the present study is no exception. Nevertheless, co-occurring ADHD symptom severity (both inattentive and hyperactive-impulsive behaviors) was comparable among the younger AIS and NS groups, as well as teacher-defined AIS and NS groups. This pattern of findings is consistent with research suggesting that AIS does not differentially predict ADHD severity compared with NS10,11 and sugge
A gross oversimplification of pathogenic processes that may index distinct neurobiological processes33 and contribute to situation specificity. Future research will need to identify distinct neurobiological substrates that contribute to individual differences in AIS.33,34 For example, previous clinical and developmental investigations have considered constructs similar to AIS (e.g., emotional lab
Arch will need to determine the best approach for conceptualizing AIS and NS (categorical vs. dimensional), evaluating data from different informants, assessing ODD symptoms, and considering different developmental periods to improve our understanding of relations between ADHD and ODD. Contextual Variables The modest convergence in group differences for the two informant-based classification syst
Nvironmental variables that in turn influence informant perceptions of symptom severity, (a) the characteristics of the emotional response are correlated within setting and (b) the expression of anger, anxiety, and depression likely share common neurobiologic pathways.NIH-PA Author Manuscript NIH-PA Author Manuscript NIH-PA Author ManuscriptJ Am Acad Child Adolesc Psychiatry. Author manuscript; a
And teacher-defined groups. These results are consistent with previous research with epidemiologic samples linking AIS and NS to CD symptoms concurrently11 and prospectively.6 Nevertheless, our findings diverge from studies that considered AIS and NS symptoms dimensionally, which found NS (but not AIS) predicted CD symptoms.7,10 It is noteworthy that these relations were observed with and without
Eatures are influenced by individual differences in neurobiology, personal experiences, and contextual characteristics.NIH-PA Author Manuscript NIH-PA Author Manuscript NIH-PA Author ManuscriptAcknowledgmentsThis research was supported in part by NIMH 1K01MH073717-01A2 (DAGD)NIH Public AccessAuthor ManuscriptMem Cognit. Author manuscript; available in PMC 2013 January 24.Published in final e

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